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Choline is an essential nutrient that affects liver, brain, and heart health

Together, BCAA catabolism in BAT is critical for the control of energy balance and glucose homeostasis through thermogenesis-dependent energy expenditure and thermogenesis-independent redox balance and insulin signaling
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Mol Psychiatry (2013).10.1038/mp.2013.138 28 AndreassenOAHarboHFWangYThompsonWKSchorkAJMattingsdalMet alGenetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci
Effect of physical training on airway inflammation in bronchial asthma: A systematic review

These findings are suggestive of a role for increased PPARA in the BWS-hepatocytes contributing to increased fatty acid oxidation, which subsequently coincides with increase in lipid peroxidation, a marker of oxidative stress
