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When the body produces and accumulates an excess of free radicals, the balance between free radicals and antioxidants is disrupted
For persistent pigmentation-driven dark circles where melanin production has been occurring over years of UV exposure or inflammation, the upstream intervention is more effective than downstream distribution inhibition alone

Similarly, for Si nano and bulk treatments, the TFC was higher in presence of 8 mg L -1 SiO 2 NPs compared to 4 mg L -1 Si bulk i.e

Figure 2 3.4.1 Probiotics impact on innate immune response Probiotics, especially Lactobacillus, have been shown to be able to attain the remarkable capability of enhancing neutrophil functionality by secreting exopolysaccharides (EPS) that activate the TLR2/MyD88 signaling pathway, thereby facilitating chemotaxis and phagocytosis
