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Additionally, MYC protein can bind to specific regions on the CTR1 promoter and regulate its transcription, thereby increasing the concentration of the copper element within liver cancer cells
During the immune exhaustion characteristic of chronic infection, an increase in CTLA-4 expression is observed, which may increase IDO activation (234)
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In addition, dimethyl fumarate ameliorated the steatosis and increased the hepatic fumarate that was minified due to the loss of Met and Tyr in vitro (Sano et al., 2021)
