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doi: 10.1111/ppl.13843 155 SunT

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10.2174/1871527315666151110130139 CNS Neurol Disord Drug Targets

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All other authors declare that there is no duality of interest associated with this manuscript

As a transcription factor, ATF4 upregulates lysine transporters (e.g., SLC7A1) and catabolic enzymes (e.g., -aminoadipate semialdehyde synthase), enhancing lysine uptake and emergency catabolism