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It has also been reported that this polyphenol positively regulates miRNA-15 and 16, which results in the induction of apoptosis in breast cancer cells (Chang and Yu, 2016)
doi: 10.1046/j.1460-9568.1998.00393.x
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Comp Biochem Physiol Part B 67:195204 Jones DP (2006) Redefining oxidative stress
Its expression level is directly associated with ferroptosis sensitivity: increased Nrf2 expression inhibits ferroptosis, while decreased expression enhances the sensitivity of cancer cells to ferroptosis inducers 58,59
doi: 10.1002/hep.24690
