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By limiting iron availability, LF also affects tumor metabolismit reduces ferritin and transferrin receptor 1 (TfR1) expression, which limits iron uptake by cancer cells, while increasing ferroportin levels, facilitating the removal of iron from cells

It shows its action by interacting with the autoinhibitory loop of c-MET as well as take advantage of small ATP binding site of c-MET to have greater specificity against the kinase molecule [113]

Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope

Nature 587 , 657662 (2020)