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More subtle improvements mood, motivation, exercise tolerance may take four to eight weeks to fully develop

Evidence snapshot: The strongest available evidence is a small Phase 1 human trial (Teichman et al., 2006) showing dose-dependent, sustained elevation of GH and IGF-1 in healthy adults

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10.1038/nrurol.2011.47 [DOI] [PubMed] [Google Scholar] 6.Pye SR, Huhtaniemi IT, Finn JD, Lee DM, ONeill TW, Tajar A, Bartfai G, Boonen S, Casanueva FF, Forti G, Giwercman A, Han TS, Kula K, et al