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Four subjects without histologically proven MASH and 13 with MASH were correctly classified as absence or presence of the disease respectively

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Their interpretation, however, is inherently integrative and iterative: each datasetgenomic variants, biochemical abnormalities, polygenic modulation, and microbiome-derived pathwaysrefines the others as new information becomes available, allowing the multidisciplinary team to recalibrate the emerging clinical model

However, results are not guaranteed, can take several months to become visible, and require consistent treatment to maintain

10.3389/fendo.2024.1431652 [DOI] [PMC free article] [PubMed] [Google Scholar] Zeeshan HM, Lee GH, Kim HR, Chae HJ (2016) Endoplasmic reticulum stress and associated ROS