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Mitochondrial dysfunction as a neurobiological subtype of autism spectrum disorder: Evidence from brain imaging

152,404 As for the AMPK signaling pathway, SMXZF, a combination of Rb1, Rg1, schizandrin, and DT-13 (6:9:5:4), exerts a neuroprotective effect on cerebral ischemia-reperfusion injury, possibly by suppressing autophagy through regulation of the AMPK/mTOR and JNK signaling pathways, both in animals and oxygen-glucose deprivation/reperfusion models

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203 Targeting PRMT7 reduces glycine decarboxylase expression, leading to the reprogramming of glycine metabolism and production of methylglyoxal, impairing the self-renewal capacity of leukemia stem cells (LSCs) and slowing the progression of leukemia

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The second reason may be that plant adaptability stabilized the working efficiency of GPX, which lead to post-transcriptional regulation, thus reducing the activity of GPX enzyme [21,22,23]