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In these models, we take into account the reaction geometry of common thiol-disulfide exchange reactions and distinguish hypothetical protein areas that might either interact with the disulfide substrate (a scaffold site) or the reducing agent (an activator site) (Fig
2017;12:e0179785
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10.1007/s00394-024-03554-0 75 MoscaA.CrudeleA.SmeriglioA.BraghiniM
BSO-treated mice were randomly divided in two subgroups: 24-hours-treated mice (n = 4 mice) or 5-weeks-treated mice (n = 4 mice)
Its expression is associated with the transcription of an alternative exon (exon 1B localized in the first intron of the GPX4 gene) that encodes for a nuclear targeting sequence [22]
