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This process prevents cascade oxidative damage to proteins, lipids, and DNAthe building blocks of healthy cells

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10.1074/jbc.274.5.3076 151 KashiwagiS.AtochinD

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The mechanism may be related to curculigoside significantly reducing AD-promoting factors (e.g., A1-42, p-tau) and increasing ferroptosis protective factors (e.g., GPX4, SLC7A11, GSH) in the hippocampus and cortex of AD mice, 574 suggesting that the natural compound curculigoside can be used as a promising therapeutic agent to improve AD by inhibiting ferroptosis

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BMC Nutr 2024;10:3

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The state of the art of redox therapeutic actions in neurodegenerative diseases

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