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Secondly, we did not have access to hepatic tissues in subjects, and cannot definitely rule out that there may be some dietary influence on flavin monooxygenasedependent conversion of TMA to TMAO

Iran J Kidney Dis 13:7486 Bruls YM, de Ligt M, Lindeboom L, Phielix E, Havekes B, Schaart G, Kornips E, Wildberger JE, Hesselink MK, Muoio D, Schrauwen P, Schrauwen-Hinderling VB (2019) Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: a randomised controlled trial

The process then helps the body utilize fat stores more efficiently

Studies have found that elevated TMAO levels correlate with impaired glucose tolerance and insulin signaling

Quick-freeze, deep-etch visualization of the axonal cytoskeleton Trends Neurosci 1986