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The immune system is critical in wound healing with immune cells promoting wound healing by secreting immunomodulatory molecules mainly cytokines, chemokines, and growth factors, facilitating cellular crosstalk and guiding tissue repair besides tackling recurring infections culminating into chronic wounds

This means that with each cell division (each time the cell undergoes mitosis), the telomeres at the ends of each chromosome shorten again

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RCTs, Randomized controlled trials