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Subsequently, MeCbl donates its methyl group to homocysteine, thereby converting it to methionine (Figure 2) while being reduced back to cobalamin

It may aid in healing of stomach ulcers, reducing gut inflammation, help with leaky gut syndrome and improving overall digestive health

Clinical Uses Cobalamin deficiency the core indication

In fact, since the cells of the gut will see the highest doses of metformin they will experience the greatest level of inhibited complex I which may explain the gastrointestinal side effects (nausea, diarrhea, anorexia) of the drug that limit its utility in many patients

Injections can be an effective way to ensure they receive enough of this vitamin.