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Additionally, mRNA with multiple chemically modified poly(A) tails was reported to maintain the translational activity of mRNA more persistently due to increased stability [63]

To facilitate synthesis of the extensive narrative data presented in Sections 6 and 7, a summary table is provided below, integrating the major psychological and physical adverse effects associated with non-medical testosterone and anabolicandrogenic steroid use across organ systems ( Table 2 )

10.1139/cjpp-2017-0533 22 ElazarM.LiuM.MckennaS

Each symptom was scored on a 4-point scale (0 = absent, 1 = infrequent, 2 = frequent, 3 = constant), yielding a total Symptom Score (SS) ranging from 0 to 30, reflecting overall symptom burden and impact on QoL

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This aggressive initial dosing saturates tissues rapidly