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Description
Jaswal JS, Keung W, Wang W, Ussher JR, Lopaschuk GD, Biochim Biophys Acta (2011) Targeting fatty acid and carbohydrate oxidation - a novel therapeutic intervention in the ischemic and failing heart

L-karnitin takviyeleri belirli ilalarla etkileime girebilir

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The acetyl-CoA enters the Krebs cycle and together with oxaloacetate give rise to citrate, which can be exported to the cytoplasm and engage in NADPH-producing reactions: the transformation of malate to pyruvate catalyzed by malic enzyme (ME1) and the oxidation of isocitrate into -ketoglutarate catalyzed by isocitrate dehydrogenase (IDH1)

The recommended dose is 50 mg/kg as a 2-3 minute slow bolus injection or infusion

doi: 10.1097/01.ta.0000162630.78386.98
