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Description
High-mobility group box 1 (HMGB1)/Toll-like receptor 4 (TLR4)/NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome signalling was measured by western blotting

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CC2026

The model includes 15 quasi-elementary reactions with corresponding rate constants, including the formation of the intermediate complex GSHH2O2 and its subsequent reactions with the formation of final products

These findings demonstrate that BM-PCa thrive under oxidative stress conditions and such that regulation of ROS and glutathione programming could be leveraged for targeting of BM-PCa progression.

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