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Description
any temperature excursion above 15C triggers irreversible peptide aggregation

Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice

Sader, N

In summary, how to specifically inhibit the amino acid metabolism of tumor cells and immunosuppressive cells in the microenvironment, and enhance the amino acid metabolism of anti-tumor immune cells such as CD8 + T cells, is an urgent problem to be solved
Epub 2001 Oct 4

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
