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Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia

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Processed and aggregated data underlying the findings are available under restricted access for reasons related to patient privacy and institutional data governance

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The immune system is a unique body system in that it is migratory and distributed, and thus it exists in many different microenvironments

The objective of this study was to evaluate the therapeutic activity of transient FAP-targeted CAR-T (FAPCAR-T) cells generated in vivo via a novelly designed LNP-mRNA system and the lung regeneration mechanism in a mouse model of bleomycin (BLM)-induced pulmonary fibrosis