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Groner AC, Cato L, de Tribolet-Hardy J, Bernasocchi T, Janouskova H, Melchers D, et al

Lim N, Singh D, Jackson S, Lake JR

Nonclinical studies detailing the efficacy of AZD2820 are sparse, though a study on body weight reduction and weight rebound in DIO mice was conducted after the clinical trial concluded (58)

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Quantification and statistics were performed within a single experiment, except for GCMS fatty acid, relative messenger RNA and MDA quantifications, which were analyzed across all replicates

It is important to note that trans -double bonds are relatively rare within mammalian membranes, while cis -double bonds are frequently abundant