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En el melanocito, la activacin del receptor MC1R incrementa el AMP cclico intracelular, que estimula la enzima tirosinasa paso limitante de la melanognesis y desplaza la sntesis hacia la eumelanina, el pigmento marrn-negro responsable del oscurecimiento de la piel (bronceado)

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Effects of ligand modification on cationic and neutral formulations were analyzed

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10.1056/NEJMoa1600177 248 ZengY.LiuJ.LiuJ.HaoY.YangN.ZhouM.et al (2020)
