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Animal protein has high levels of all the essential amino acids, thus it can trigger excessive body production of IGF-1, whereas plant protein does not
Thus, microbial Trp metabolites are expected to be a feasible intervention site to inhibit osteoporosis progression through the gutendocrinebone axis

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Identifier NCT01889667, Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Multiple Oral Bedtime Doses of ORMD-0801 in Adult Patients With Type 2 Diabetes Mellitus (T2DM) , (2013)
