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Description
In adult patients receiving TPN, the lack of carnitine in nutrition solutions contributes to deficiency, impacting fatty acid oxidation

Patients often exhibit structurally abnormal, swollen mitochondria with disrupted cristae, impaired mitochondrial recycling (a process called mitophagy), and chronically elevated levels of reactive oxygen species

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ha, Choi, B
Norenberg MD, Rama Rao KV, Jayakumar AR (2009) Signaling factors in the mechanism of ammonia neurotoxicity

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