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All the authors contributed to drafting and editing the manuscript

10.1016/0140-6736(91)92978-B Lancet 98 McLachlanD

2010;20:S24S28

This coordination geometry is essential for the biological activity observed in research models

Supplemental Se may also promote inhibition of cell growth and apoptosis by multiple mechanisms, including the enhanced accumulation of Se-metabolites that could be toxic to cells (75, 303)

Both increases and reductions in resting state functional connectivity have been reported in relation to disease severity in PD, with the most consistent findings including reduced connectivity within the posterior putamen