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The impact of hypoxia on cytosolic NADP redox dynamics had remained less clear, since lack of oxygen as an electron sink causes metabolic reduction, but also boosts H 2 O 2 production and glutathione oxidation in different phases of the hypoxic episode [37]
[DOI] [PubMed] [Google Scholar] 82.Pfohl-Leszkowicz A., Manderville R.A
8 Characterizing the metabolome of neurons from aging brains
Consistent with this, one report showed that angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers prevent the development of albuminuria in STZ-induced diabetic rats in parallel with prevention of increased expression of the p47phox component of NAD(P)H oxidase and production of its oxidative products [40]
A GAPDH-mediated trans-nitrosylation pathway is required for feedback inhibition of bile salt synthesis in rat liver
Living near highways, factories, or airports increases exposure to pollutants
