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DNA synthesis and cell metabolism Intracellular conversion of vitamin B 12 to two active coenzymes, in mitochondria and adenosylcobalamin in the cytoplasm, is necessary for the homeostasis of methylmalonic acid and homocysteine, respectively
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Pernicious anemia, an autoimmune condition, prevents the body from absorbing B12 due to a lack of Intrinsic Factor (IF) in the stomach
