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Specifically, it produces no IGF-1 elevation (avoiding proliferative concerns), no negative impact on glucose metabolism (avoiding diabetes risk), no fluid retention or edema, and no concerning patterns of joint pain that can occur with growth hormone

Taub et al

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Microscopy The tissue specimens were immediately fixed in buffered formalin (pH 7.4), for 24 hours, dehydrated, and embedded in paraffin wax