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Moreover, assessing immunogenicity is complex, and such assessments should account for the detection of new drug-specific responses
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Hecht SS, C-hB C, Ohmori T et al (1980) Comparative Carcinogenicity in F344 Rats of the Tobacco-specific Nitrosamines, N-Nitrosonornicotine and 4-(N-Methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone1
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Avoid repeated freezethaw cycles
