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This leads to elevated and unregulated activation of PKC enzymes and the consequent disruption in normal cellular growth and proliferation control leading, ultimately, to neoplasia

Metabolite identities in the HILIC-pos, HILIC-neg, and C18-ng methods were confirmed using authentic reference standards

Apart from treatment resistance, another issue encountered is metastasis of malignant cells
[DOI] [PMC free article] [PubMed] [Google Scholar] 215.Mancini M., Chung K., Zajack A., Martini D.N., Ramsey K., Lapidus J., Horak F.B., Nutt J.G