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The antioxidant effect of GPX4 depends on the presence of GSH as a reducing agent, with two GSH reducing one LOOH

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Missing values were imputed by random sampling of the lower end of the normal distribution (width 0.3 and downshift 1.8) in total matrix

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An improved understanding of the regulatory interfaces that exist between blood and brain may provide novel and more effective strategies to treat neurological disorders

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Epitalon continues to be a subject of scientific interest and promises new possibilities in the fight against aging, but its application requires a careful approach and professional medical advice.

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It has been declared, that neurotoxic 6-hydroxydopamine (and also superoxide radical) is able to release free iron from ferritin which in turn may participate in Fenton chemistry, forming ROS and initiating lipid peroxidation (Monteiro and Winterbourn 1989)

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Heterogeneity and penumbra of white matter hyperintensities in small vessel diseases determined by quantitative MRI

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