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Integrating Network Pharmacology, Transcriptomics to Reveal Neuroprotective of Curcumin Activate PI3K / AKT Pathway in Parkinsons Disease

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DOI: 10.7326/0003-4819-146-8-200704170-00152 BC Provincial Academic Detailing Service

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These genes are associated with copper efflux and oxidation, respectively

As it has been established, activated JNK is present in neurons and dystrophic neurites of both mice and brain AD models, which coincides with phosphorylation of protein insulin receptor substrate-1 (IRS-1) and tau, deposition of amyloid plaques and synapthophysin loss [301]