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doi: 10.1016/s0731-7085(02)00456-9

Mechanisms of specificity in neuronal activity-regulated gene transcription

Individuals with specific single nucleotide polymorphisms (SNPs) impacting B12 absorption may benefit more from certain forms of Vitamin B12. However, since these SNPs are not typically included in commercial tests, individuals may need to experiment with different B12 forms sequentially or opt for a supplement containing a combination of all three naturally occurring forms of B12 for potentially faster clinical improvements

Manda et al., 2010

Further, the authors noted that participants who received epithalamin had lower rates of ischemic heart disease as well as improved levels of key biomarkers such as cortisol and insulin

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