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Respirology 22 , 240250 (2017)

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Wang Y, Wang W, Su L, Ji F, Zhang M, Xie Y, et al

BMJ Open 13 , e068480 (2023)

For metabolic analysis of cultured cancer cells and tumours, frozen tumour tissue was homogenized in 80% methanol containing 20 mM NEM using a Precellys cold tissue homogenizer (Bertin) at a ratio of 20 mg tissue to 1 ml solvent

Therefore, the discrepancy of the histological results obtained in acromegalic animals and humans may be, at least partly, due to significantly more pronounced GH excess in animals compared to humans