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Notably, accumulating evidence now demonstrates that cancer-associated metabolic changes are not merely supportive but can directly induce genome instability at multiple levels

Importantly, we further identified HO-1 mitochondrial translocation as a key mechanism for oxidative stress-induced mitochondrial iron overload and ROS accumulation

Stoyanovsky DA, Jiang J, Murphy MP et al (2014) Design and synthesis of a mitochondria-targeted mimic of glutathione peroxidase, mitoebselen-2, as a radiation mitigator

As levels rise, these symptoms can improve within a few days or weeks

10.3390/brainsci12101287 23 MorganH

doi:10.23736/S0391-1977.18.02824-9 Kumar A, Barki S, Raghav V, Chaturvedi A, Kumar K