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Calkins, C

The V-ATPase B1-subunit promoter drives expression of Cre recombinase in intercalated cells of the kidney

The GHK tripeptide sequence was first isolated from human plasma in the 1970s

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Succinate accumulation inhibits -KGdependent TET and JMJD demethylases, promoting DNA and histone hypermethylation, whereas reduced -KG availability further constrains demethylation and limits enhancer plasticity

ED is commonly associated with chronic illnesses, especially diabetes, hypertension, and depression
