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Cohen, J

These responses lead to altered cellular phenotypes, which may scale up to cause structural and functional abnormalities at the organismal level (Zeng et al., 2023) (Figure 1)

ROS damage not only nuclear DNA but also mitochondrial DNA (mtDNA) [1]
One study revealed that mitochondrial AC deficiency and fatty acid metabolism disorders were not related to fatigue in patients with MS (53)

[DOI] [PubMed] [Google Scholar] 63.Crimarco A., Springfield S., Petlura C., Streaty T., Cunanan K., Lee J., Gardner C.D
