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Prescribing information for BVd includes a Boxed Warning for ocular toxicity, including corneal vision deterioration
Moreover, some inflammatory cytokines are known to reduce IGF-1 levels in animal models [215]

Watch for worsening pain and spreading redness beyond the immediate area after 48 to 72 hours, fever, a hard warm lump, or systemic allergic symptoms such as hives, facial swelling, throat tightness, or breathing difficulty

10.1165/rcmb.2013-0211OC [DOI] [PubMed] [Google Scholar] 41.Habib AM, Nagi K, Thillaiappan NB, Sukumaran V, Akhtar S

Giving vitamin B12 when it is not needed may lead to unnecessary nutritional excesses or imbalances

Segerlantz M, Bramnert M, Manhem P, Laurila E, Groop LC
