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Ozone therapy increases red blood cell oxygen delivery, activates immune cells, and has documented anti-inflammatory and anti-microbial effects

Immune cells use ROS to sustain their functions and need adequate levels of antioxidant defenses to avoid harmful effects caused by excessive ROS production, since accurate balance between ROS and intracellular antioxidants is essential for a normal function of the cell (Banjac et al., 2008

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10.1186/1479-5876-7-15 190 ZhouT.BendaC.DuzingerS.HuangY.LiX.LiY.et al (2011)

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