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Glutathionylation of the L-type Ca2+ channel in oxidative stress-induced pathology of the heart

The antizyme proteins interact with ODC1 monomers preventing formation of functional homodimers while simultaneously altering the conformation of the monomers so that they are recognized by the proteasome

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On HFHSD, insulin tolerance test (ITT)showed significantly higher blood glucose levels of Aldh2 KI and HE mice than WT mice, indicating increased insulin resistance (Fig