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How can insulin resistance cause Alzheimers disease

However, the lack of extensive human studies makes it too early to definitively confirm these benefits

Excitotoxic damage via the upregulation of NMDA receptors highly depends on the cellular energy state, with ALC inducing ureagenesis that causes a decrease in blood and brain level of ammonia as well [79]

[64] In other diseases, such as Alzheimer's, the evidence on vitamin E supplementation is also mixed

However, administration of pyruvate has been shown to correct some of these central issues observed in neurodegeneration

Pillich RT, Scarsella G, Risuleo G
