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Peffer, R

To find out the pathways involved, we initially evaluated previously known glutathione degrading enzymes since glutathione is a -Glutamyl tri-peptide, and previously known transporters for glutathione and peptides

Combining gamma-tocopherol and aspirin synergistically suppresses colitis-associated colon tumorigenesis and modulates the gut microbiota in mice, and inhibits the growth of human colon cancer cells

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The maintenance of a high intracellular GSH/GSSG ratio, typically exceeding 100:1 in healthy cells, is critical and is actively managed by the enzyme glutathione reductase (GR)

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