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Animal experiments All in vivo procedures were conducted according to the guidelines from the regional Ethics Committee for Animal Research, Skane, Sweden (permit nos

Increased oxidative stress due to smoking contributes to atherosclerosis by inducing cell proliferation, cell hypertrophy, and apoptosis, either directly through vascular endothelial damage or through activation of various intracellular signaling pathways

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Investigating the mechanisms by which oxidative stress affects epigenetic modifications in sperm and how these modifications may influence embryonic development and offspring health is a promising area of research that could have significant implications for reproductive medicine