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hCOs have also been used to model the role that MOR receptors have on pain signaling mechanisms (Fernandes et al., 2022)
1-pyrroline-5-carboxylic acid synthase, which is encoded by the aldehyde dehydrogenase 18A1, is responsible for the conversion of glutamate to pyrrole acid, which is then converted to proline by pyrroline-5-carboxylate reductase
64 (4), e12475
2000;15(7):15621567 [DOI] [PubMed] [Google Scholar] 8
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