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However, loss of GPX1 induced the expression of cyclooxygenase-2 and release of prostaglandins [119]

In line with this observation, the pre-administration of DSePA (2 mg/Kg bodyweight) for five consecutive days significantly improved the 30-day survival of mice against the lethal dose (-rays, 10 Gy) of WBI by preventing lipid peroxidation, DNA damage, and apoptosis in the radiosensitive organs like the spleen and small intestine [88, 89]

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We found that GPX3 overexpression could significantly up-regulate the phosphorylation of ERK1/2 but had a weak effect on JNK1/2 and p38

A plant DJ-1 homolog is essential for Arabidopsis thaliana chloroplast development

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