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J Hypertens 33: 11281136, 2015

[PubMed] [Google Scholar] 26.Li H., Feng S.J., Zhang G.Z., Wang S.X
However, targeted nose-to-brain, or intranasal (IN), approaches have begun to emerge that allow CNS-specific delivery of therapeutics via the trigeminal and olfactory nerve pathways, laying the foundation for improved alternatives to systemic drug delivery

doi: 10.1186/1471-2202-11-51 114

Thus, in order to maintain high serum values, a continuous vitamin B6 supply is necessary

Temporal organization of pineal melatonin signaling in mammals