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Although the pathogenesis of these liver diseases is complex, both show a similar spectrum of liver pathology that ranges from steatosis (i.e., the buildup of fat) to steatohepatitis (i.e., the inflammatory state), cirrhosis (i.e., the fibrosis/scarring) and hepatocellular carcinoma (Toshikuni et al., 2014)

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Jan 1977;113(1):31-36

However, animal studies dont always predict what will happen in humans

Observational studies have consistently shown the positive effects of weight loss, as indicated by imaging biomarkers, although relatively few randomized clinical trials have reported histological endpoints