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[DOI] [PMC free article] [PubMed] [Google Scholar] 363.Gou Z., Li F., Qiao F., Maimaititusvn G., Liu F

& Winkler, A
Stability of protein pharmaceuticals: an update

Int J Adv Res Sci Commun Technol

In the CENTAUR trial which was a placebo-controlled, double-blind, multicenter and randomized study, the effectiveness and safety of sodium phenylbutyrate-taurursodiol (PB-TURSO) were confirmed in the patients with ALS (21)

After having first improved, one patient subsequently worsened, with clinical symptoms and a new pattern of brain hypometabolism (102)
