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It is among the most referenced melanocortin analogs in receptor-pharmacology research literature
Drew BG, Duffy SJ, Formosa MF, Natoli AK, Henstridge DC, Penfold SA, et al
FEMS Microbiol Lett 13, 201205
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[DOI] [PubMed] [Google Scholar] 63.Gonzlez-Loyola A., Petrova T.V
There are differences in circadian rhythm, hormones, and the microbiome as well, along with inflammatory markers that correlate with depression
