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MtROS are mobilized into the cytoplasm and then activate protein kinase C (PKC), subsequently activating NADPH oxidase and producing more ROS, which together with mtROS induces NETosis

Responsiveness of One-Carbon Metabolites to a High-Protein Diet in Older Men: Results from a 10-Wk Randomized Controlled Trial. Nutrition (Burbank, Los Angeles County, Calif.), vol
It was recently shown that antioxidants can prevent loss of HSCs self-renewal potential in several contexts, such as aging or after exposure to low doses of irradiation, suggesting that antioxidants can be used to maintain HSCs functional properties upon culture-induced stress [20, 21]

doi: 10.1055/a-0723-3749 221 KadoglouNPVrabasISKapelouzouALampropoulosSSailerNKostakisAet al

Oxidative Stress and the Role of NADPH Oxidase in Glaucoma

Panels D, E, and F show the corresponding concentration curves for GSH
