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Thus, upon careful selection of the MOA, the inclusion of ferroptosis-inducing agents within a clinically relevant treatment protocol is feasible and can outperform standard-of-care chemotherapy in high-risk NB

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Twenty Elav4 + clusters correspond to differentiated neuronal cell populations ( Elav4 + , Sy65 + and Scna + ), two clusters (Neuro_1 and Neuro_2) constitute undifferentiated neuronal cells ( Elva4 + but Sy65 ) and four clusters represent non-neuronal types (Fig

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used angiotensin (Ang) II injection to simulate a hypertension-mediated cardiac remodeling model and found that ferroptosis occurred and that the protein expression of GPX4 and xCT was downregulated in the myocardium
